EurekAlert!: Researchers identify Achilles’ heel in lung cancer through common p53 genetic mutation
A team of researchers at VCU Massey Comprehensive Cancer Center has identified a new pathway through which mutations in the tumor suppressor p53 gene—found very frequently in human tumors—hijack DNA ...
Researchers identify Achilles’ heel in lung cancer through common p53 genetic mutation
Researchers have elucidated the role of the p53 gene in ulcerative colitis. The study suggests a potential new drug target to stop disease progression to cancer. Researchers in the lab of Michael ...
GEN: Ulcerative Colitis Association with Cancer Risk Linked to p53 Tumor Suppressor Gene
Ulcerative Colitis Association with Cancer Risk Linked to p53 Tumor Suppressor Gene
News Medical: Researchers uncover why the TP53 gene is especially prone to mutations in cancer
Researchers uncover why the TP53 gene is especially prone to mutations in cancer
TP53 mutations are crucial in cancer development and treatment response, influenced by genetic and environmental factors. In CLL and AML, TP53 serves as a significant prognostic marker, affecting ...
The gene p53 acts as a tumor suppressor and often is called the ‘guardian of the genome.’ This gene is central to maintaining genomic stability, which prevents mutations from accumulating and leading ...
As we age, our cells accumulate genetic changes—mutations—some of which open the door to cancer. Scientists call these mutations "oncogenic," meaning "tumor-producing." By our senior years, we each ...
The American Journal of Managed Care: TP53 Mutations Remain Important Research Focus in Cancer
The Buffalo News: AACR 2026: Roswell Park tests mechanism-based strategy for p53 cancers