A hallmark of cancerous cells is an abnormal number of chromosomes or chromosome arms, known as aneuploidy. While aneuploidy is detrimental to regular cells, it occurs in as many as 90% of tumors. How ...
MSN: Cancer-promoting DNA circles hitchhike on chromosomes to spread to daughter cells
Small, cancer-associated DNA circles "hitchhike" on chromosomes during cell division to spread efficiently to daughter cells by co-opting a process used to maintain cellular identity through ...
Osaka, Japan -- When a cell divides--a process known as mitosis--its chromosomes need to be separated and evenly distributed into the newly created daughter cells. Although this is known to be ...
For a living cell to divide successfully, each daughter cell must inherit the correct genetic material. In eukaryotes, segregation of duplicated chromosomes is performed by the mitotic spindle, a ...
Yale Environment 360: Eliminating extra chromosomes in cancer cells prevents tumor growth
Cancer cells with extra chromosomes depend on those chromosomes for tumor growth, a new Yale study reveals, and eliminating them prevents the cells from forming tumors. The findings, said the ...
Singularity Hub: Human Artificial Chromosomes Could Ferry Tons More DNA Cargo Into Cells
The human genetic blueprint is deceptively simple. Our genes are tightly wound into 46 X-shaped structures called chromosomes. Crafted by evolution, they carry DNA and replicate when cells divide, ...
A tension-sensitive "fail safe" protein helps make sure that when our cells divide the two resulting cells inherit the normal number of chromosomes, researchers from the University of Washington and ...