It has been shown that high resolution HLA typing (HLA-A, HLA-B, HLA-C, HLA-DRB1, HLA-DQB1 and HLA-DPB1) may be relevant in transplantation to identify a full match, even when the donor is related.
Some class I MHC genes encode nonclassical (ie, not CD8-binding) MHC molecules, such as HLA-G (which may play a role in protecting the fetus from the maternal immune response) and HLA-E (which presents peptides to certain receptors on natural killer [NK] cells).
Human leukocyte antigen (HLA) are proteins found on most cells in the body. HLA are used by doctors to help match blood stem cell donors with patients.
An HLA blood test examines human leukocyte antigens (HLA), which are proteins found on the surface of most cells in the body. This test provides detailed information about an individual’s unique genetic tissue type.
HLA are protein structures that are found on most of the cells in your body and their role is to help your immune system to identify foreign items. This is important for your body to stay healthy.
Human leukocyte antigen (HLA), any of numerous antigens involved in the major histocompatibility complex (MHC) in humans. The HLA genes, of which more than 200 are known, encode the cell-surface proteins of the MHC.
The genetics, nomenclature, and typing of HLA, as well as the relationships between HLA and rheumatic disease, are discussed here. The older nomenclature that may still be encountered in the literature is defined.
What are donor-specific HLA antibodies, and how are they relevant to HLA testing? Donor-specific human leukocyte antigen (HLA) antibodies are recipient antibodies directed against HLA antigens that are expressed by donated organs or tissues.