Here, we provide the detailed structure of mTOR, its complexes, and the comprehensive role of upstream regulators, as well as downstream effectors of mTOR signaling cascades in the metabolism,...
Notably, mTOR plays a pivotal role in cardiovascular health and disease, particularly in the onset and progression of cardiac conditions. In this review, we discuss mTOR’s structure and function as well as the regulatory mechanisms of its associated signaling pathways.
Many aspects of mTOR function and regulation have only recently been elucidated, and many more questions remain unanswered. In this review, we provide an overview of our current understanding of the mTOR pathway and its role in growth, metabolism, and disease.
The MTOR gene provides instructions for making a protein called mTOR. Learn about this gene and related health conditions.
MTOR (Mechanistic Target Of Rapamycin Kinase) is a Protein Coding gene. Diseases associated with MTOR include Smith-Kingsmore Syndrome and Focal Cortical Dysplasia, Type Ii.
Embedded in a complex network of signaling pathways, mTOR dysregulation is implicated in the onset and progression of a range of human diseases, including metabolic disorders such as diabetes and cardiovascular diseases, as well as various cancers. mTOR also has a notable role in aging.
mTOR: Its Critical Role in Metabolic Diseases, Cancer, and the Aging ...
What is mTOR? mTOR stands for the “mechanistic target of rapamycin.” It’s a signaling pathway in your body that acts like a master switch for growth. When activated, mTOR tells your body to start building. More specifically, it is used to increase protein synthesis and create new muscle tissue.