The Encylopedia of DNA Elements (ENCODE) Project launched in 2003 with the long-term goal of developing a comprehensive map of functional elements in the human genome. These included genes, biochemical regions associated with gene regulation (for example, transcription factor binding sites, open chromatin, and histone marks) and transcript isoforms. The marks serve as sites for candidate cis ...
PRO-cap in peripheral blood mononuclear cell Homo sapiens peripheral blood mononuclear cell Lab: Haiyuan Yu, Cornell Project: ENCODE Library construction method: capped RNA enrichment Experiment ENCSR386UFU
ENCODE experiments must satisfy the data production guidelines (see the Data production guidelines link, Useful Links section below); raw data produced by the experiments are available at the ENCODE portal (see the Experiment matrix link, Useful Links section below).
About the ENCODE Consortium The Encyclopedia of DNA Elements (ENCODE) Consortium is an ongoing international collaboration of research groups funded by the National Human Genome Research Institute (NHGRI). The goal of ENCODE is to build a comprehensive parts list of functional elements in the human genome, including elements that act at the protein and RNA levels, and regulatory elements that ...
The ENCORE project aims to study protein-RNA interactions by creating a map of RNA binding proteins (RBPs) encoded in the human genome and identifying the RNA elements that the RBPs bind to.
The ENCODE Consortium uses these measures to set standards detailing the criteria for excellent, passable, and poor data. On the ENCODE portal, data that do not meet the minimum cutoff values are flagged according to severity of the error; examples of errors include low read depth, poor replicate concordance, or low correlation.