The fibrous proteins and ground substance produced by fibroblasts are what constitute the extracellular matrix (ECM), which makes up the bulk of connective tissue. The ECM has many roles within ...
The composition of the extracellular matrix differs between tissue types. Though its main function is to provide an essential scaffold for cells, the extracellular matrix also regulates processes by ...
A new 3D connective tissue model gives researchers a sophisticated tool to understand the underlying mechanisms of connective tissue disorders and test potential treatments. To find treatments for ...
For in vitro cellular assays, the extracellular matrix—the material between cells—often is overlooked, but changes within this microenvironment affect cells’ proliferation and differentiation and, ...
Despite its compact structure—composed of only three amino acids—this endogenous tripeptide has been repeatedly situated at the intersection of regenerative biology, extracellular matrix dynamics, ...
The Brown Daily Herald: Brown researchers study connective tissue mechanics using new cellular model
University researchers have developed a new connective tissue model to study disorders like fibrosis, a type of scarring that occurs when damage to the body causes normal tissue to be replaced by hard ...
We will use porous media theory to examine the principles governing fluid flow and mass transfer in the extracellular matrices of the body and show how these principles can be use in tissue ...
News Medical: Connective tissue protein promotes immune responses that fight bacterial infections
A connective tissue protein known to support the framework of organs also encourages immune responses that fight bacterial infections, while restraining responses that can be deadly in the condition ...