Ambroxol is a mucolytic compound and the main ingredient of over-the-counter cough medicines sold in many countries. Syrup, tablet, and other forms are used at doses of 30 to 120 mg per day to reduce or thin mucous secretions and ease sore throat pain. The most common side effects are gastrointestinal. Ambroxol is unavailable in North America.
Bouscary A, Quessada C, Mosbach A, Callizot N, Spedding M, Loeffler JP, Henriques A. Ambroxol Hydrochloride Improves Motor Functions and Extends Survival in a Mouse Model of Familial Amyotrophic Lateral Sclerosis.
Early initiation of ambroxol treatment diminishes neurological manifestations of type 3 Gaucher disease: A long-term outcome of two siblings. Eur J Paediatr Neurol. 2021 May;32:66-72.
Maegawa GH, Tropak MB, Buttner JD, Rigat BA, Fuller M, Pandit D, Tang L, Kornhaber GJ, Hamuro Y, Clarke JT, Mahuran DJ. Identification and characterization of ambroxol as an enzyme enhancement agent for Gaucher disease. J Biol Chem. 2009 Aug 28;284 (35):23502-16. Epub 2009 Jul 3 PubMed. Recommends Please login to recommend the paper.
Researchers in Canada recently evaluated the ability of the chaperone ambroxol to stimulate GBA activity in a small Phase 2 Parkinson’s study, and a similar trial of ambroxol is starting up in London.
EXCELSIOR: ¿Te quita la tos? Ambroxol: usos, para qué sirve y por qué algunos doctores no la recomiendan
El ambroxol es un fármaco ampliamente utilizado en el tratamiento de diversas afecciones respiratorias, especialmente aquellas que implican la producción excesiva de moco. Su capacidad para ...
¿Te quita la tos? Ambroxol: usos, para qué sirve y por qué algunos doctores no la recomiendan